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  • Include sire of Albrecht 1st Alw (Feb 20, 6th LRL). Owner, Daniel T. O'Ryan; Breeder, Fitzhugh, LLC...
  • Street Sense sire of Castaway 1st Southwest S. (G3) (Feb 20, 8th OP). Owner, Magnier, Mrs. John, Tabor, Michael and Smith, Derrick; Breeder, Hertrich/McCarthy Livestock LLC...
  • Latent Heat sire of Cowcutta 1st Mdn (Feb 20, 10th TP). Owner, Patrick K. Preston; Breeder, Hedgewood Farm...
  • Mizzen Mast sire of Wicked Mizz 1st Mdn (Feb 20, 3rd PRX). Owner, Green Lantern Stables LLC; Breeder, Y-Lo Racing Stables, LLC...
  • Monarchos sire of Dance With Monarch 1st Alw (Feb 20, 10th OP). Owner, Jayaraman, Dr. K. K. and Jayaraman, Dr. Vilasini D.; Breeder, John C. Oxley...
  • Stormy Atlantic sire of Stormy Lucy 1st Alw (Feb 20, 8th GG). Owner, Frank L. Gaunt; Breeder, Mercedes Stable, LLC...
  • Montbrook sire of Lightning Road 1st Alw (Feb 20, 3rd BEU). Owner, Equinox, Inc.; Breeder, Kinsman Farm...
  • Eddington sire of Secret Circle 1st Southwest S. (G3) (Feb 20, 9th OP). Owner, Watson, Karl, Pegram, Michael E. and Weitman, Paul; Breeder, Willmott Stables...
  • Hard Spun sire of Hard Facts 1st Alw (Feb 20, 8th LRL). Owner, Harry C. and Tom O. Meyerhoff LLC; Breeder, Woodford Thoroughbreds, LLC...
  • Dynaformer sire of Starformer 1st Alw (Feb 20, 9th GP). Owner, Juddmonte Farms, Inc.; Breeder, Juddmonte Farms Inc....
  • Kela sire of Moonshine Bay 1st Alw (Feb 20, 3rd TP). Owner, Ted W. Lucas; Breeder, Raymond Kolar...
  • Freud sire of Freud's Notebook 1st Alw (Feb 20, 5th AQU). Owner, Bree-N-Me; Breeder, Mr. & Mrs. P. A. Everard...
  • Harbor the Gold sire of L G Jet 1st Oregon Thoroughbred Breeders Derby (Feb 20, 6th PM). Owner, Georgianne Hammrich; Breeder, Leonard Hammrich...
  • Posse sire of Law Enforcement 1st Hollie Hughes S. (Feb 20, 8th AQU). Owner, Camelia J. Casby; Breeder, Camelia Casby...
  • Medaglia d'Oro sire of Anaan 1st Alw (Feb 20, 7th HOU). Owner, Jose Luis Espinoza; Breeder, Two Sisters' Farm, Inc....
  • Bluegrass Cat sire of Enchante 1st Alw (Feb 20, 9th PRX). Owner, Will, Samantha and David; Breeder, David Will...
  • Giant's Causeway sire of Giant Sensation 1st Alw (Feb 20, 3rd AQU). Owner, Overbrook Farm and Andrew Farm; Breeder, Southern Equine Stables, LLC & Hill 'n'Dale Equine Holdings, Inc....

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Genomics could be used to address equine health issues

Posted: Wednesday, February 07, 2007 5:52 PM

The first draft of a horse’s genome—or genetic material—sequence has been deposited in public databases and is available for use by biomedical and veterinary researchers around the world, the international Horse Genome Sequencing Project announced on Wednesday.

The $15-million effort to sequence approximately 2.7-billion DNA base pairs in the genome of the horse was funded by the National Human Genome Research Institute. A team led by Dr. Kerstin Lindblad-Toh at the Eli and Edythe L. Broad Institute of the Massachusetts Institute of Technology and Harvard University carried out the sequencing and assembly of the horse genome.

Sequencing of the domestic horse genome began in 2006 and built upon a ten-year effort to use genomics to address important health issues for equines.

DNA was used in the sequencing efforts from a Thoroughbred named Twilight, who is stabled at Cornell University in New York along with band of horses that have been selected and bred for more than 25 years to study the mechanisms that prevent maternal immunological recognition and destruction of a developing fetus during pregnancy.

There are more than 80 known genetic conditions in horses that are genetically similar to disorders seen in humans, including musculoskeletal, neuromuscular, cardiovascular, and respiratory diseases.

Over the next several months, researchers plan to further improve the accuracy of the horse genome sequence and expect to deposit an even higher resolution assembly in public databases. Comparing the horse and human genomes will help medical researchers learn more about the human genome and also will serve as a tool for veterinary researchers to better understand the disease that affects equines.

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